News Ticker with Links

Research & Clinical Trials

Introduction

The emphasis of research work is mainly to develop newer surgical techniques and development of formulations for treatment of various diseases for which there are limitations in the modern system of medicine. Medical management of urinary calculus and wound healing is the challenging task for modern medicine. In the traditional system of medicine number of herbs or formulations derived from them are prescribed to treat these conditions. However, such formulations are not acceptable at a global level, mainly due to the lack of standardization protocol to validate uniformity and consistency. There are a number of publications on the preclinical aspect of such formulations; however, these leads are not validated further for clinical use or application. In addition, on such formulations derived from natural products hardly systematic prospective clinical studies have been carried out to understand safety, efficacy, exact indication and limitations of the treatment following GCP norms. Under this scenario during the last decade, it was decided to undertake research projects based on traditional Ayurvedic knowledge, employing natural products for the development of formulations for the treatment of Kidney stone and wound healing at the ACE hospital research centre.

Recognition
  • Based on infrastructure and research achievements in this institution, Scientific Industrial Research Organization (SIRO) status was awarded by the Department of Science and Technology (DST), Government of India.
  • To conduct the clinical research as per global and national norms, Institutional Ethics Committee (IEC) was constituted and is registered with the Central Drugs Standard Control Organization, New Delhi (CDSCO).
  • The institution is recognized by Maharashtra University of Health Sciences (MUHS), Nasik, for Postgraduate studies in Urology.
  • The financial support was awarded for the research project on ‘Herbmed’- a herbal formulation for the treatment of Urolithiasis by Department of Science and Technology, Government of India.

Collabaration

Drug development and clinical research is a multidisciplinary activity and inputs from various scientific disciplines are essential. In order to increase the scope of research work, the collaborations with national and international Laboratories viz.

  • Indian Institute of Technology, (IIT) Mumbai
  • Indian Drugs Research Association and Laboratory, Pune.
  • University of Pune
Clinical Trials

A Clinical trial is a core activity of the research department. In view of this number of clinical trials were completed in the past and some are ongoing. We are conducting In house clinical trials as well as Sponsor trials by various renowned National & International pharmaceutical companies. All these trials are conducted after approval of IEC and registration with CTRI as per standard norms.

Sr.no
Title of project
Sponsor
1.
“Efficacy and Tolerability of Intravenous Administration of Ceftazidime + Clavulanic acid in Complicated Urinary Tract Infection and Pyelonephritis”
Ranbaxy Pvt.Ltd, Bombay
Publications:  The research work carried out under various projects like developing new surgical techniques and drug development are being published in SCI journals of repute. So far 18 research papers were published in a renowned journal like:
Presentations: The research work carried out under various projects is being presented at National & International Conferences, Seminars, etc. Some of them are
Patents: 
Introduction

Ace Hospital the healthcare and research institute has engaged in
continued research that has lead to the development and innovation of affordable alternatives for treatment of kidney disorders , surgical wounds and infectious diseases. Research in modern medicine , clinical studies , randomized double blind trials have been undertaken hand in hand with studies in traditional medicine.
Pioneering the fusion research in traditional and modern medicine has heralded a novel concept of “Alloayur” medicine. This has brought a new outlook that has the potential to make a paradigm shift in the treatment modalities on various ailments.
Research on traditional medicine stretched into the epidemic of Covid 19 and a formulation on the same was designed. A randomized , controlled trial established the efficacy of the same. It demonstrated the ability to boost the immune function and significantly decrease the viral load.
The polyherbal formulation to boost immunity and manage infections such as Covid19 has been applied for patenting.
Similar work on NAFLD- fatty liver is showing encouraging results and once again if integrated with the modern system would a go a long way in harnessing the potential of transdisciplinary research and innovations. Clinical studies are completed and the polyherbal formulation used in the study has shown very encouraging results.
Clinical studies on role of Gut Health in the management of CKD ( Chronic Kidney Disease) with polyherbal formulation are ongoing . The results are encouraging and would provide an alternative modality to manage cases of CKD.

Recognition
  • Based on infrastructure and research achievements in this institution, Scientific Industrial Research Organization (SIRO) status was awarded by the Department of Science and Technology (DST), Government of India.
  • To conduct the clinical research as per global and national norms, Institutional Ethics Committee (IEC) was constituted and is registered with the Central Drugs Standard Control Organization, New Delhi (CDSCO).
  • The institution is recognized by Maharashtra University of Health Sciences (MUHS), Nasik, for Postgraduate studies in Urology.
  • The financial support was awarded for the research project on ‘Herbmed’- a herbal formulation for the treatment of Urolithiasis by Department of Science and Technology, Government of India.

Collabaration

Drug development and clinical research is a multidisciplinary activity and inputs from various scientific disciplines are essential. In order to increase the scope of research work, the collaborations with national and international Laboratories viz.

  • Indian Institute of Technology, (IIT) Mumbai
  • Indian Drugs Research Association and Laboratory, Pune.
  • University of Pune
Clinical Trials

A Clinical trial is a core activity of the research department. In view of this number of clinical trials were completed in the past and some are ongoing. We are conducting In house clinical trials as well as Sponsor trials by various renowned National & International pharmaceutical companies. All these trials are conducted after approval of IEC and registration with CTRI as per standard norms.

Sr.no
Title of project
Sponsor
1.
“Efficacy and Tolerability of Intravenous Administration of Ceftazidime + Clavulanic acid in Complicated Urinary Tract Infection and Pyelonephritis”
Ranbaxy Pvt.Ltd, Bombay
Publications:  The research work carried out under various projects like developing new surgical techniques and drug development are being published in SCI journals of repute. So far 18 research papers were published in a renowned journal like:
Presentations: The research work carried out under various projects is being presented at National & International Conferences, Seminars, etc. Some of them are
Patents: 

A Clinical trial is a core activity of the research department. In view of this number of clinical trials were completed in the past and some are ongoing. We are conducting In house clinical trials as well as Sponsor trials by various renowned National & International pharmaceutical companies. All these trials are conducted after approval of IEC and registration with CTRI as per standard norms.

Sr.no
Title of project
Sponsor
1.
“Efficacy and Tolerability of Intravenous Administration of Ceftazidime + Clavulanic acid in Complicated Urinary Tract Infection and Pyelonephritis”
Ranbaxy Pvt.Ltd, Bombay
Publications:  The research work carried out under various projects like developing new surgical techniques and drug development are being published in SCI journals of repute. So far 18 research papers were published in a renowned journal like:
Presentations: The research work carried out under various projects is being presented at National & International Conferences, Seminars, etc. Some of them are
Patents: